Hopes and fears for vaccination

NPR recently told a disappointing story about how a fourth mRNA vaccine shot brings quickly diminishing returns, a pundit suggesting that it is not plausible for us to receive shots with sufficient frequency and targeting to have much certainty in evading the SARS-CoV-2 du jour. Accepting that, perhaps one may as well enjoy throwing caution to the wind while the protection from one's booster is at its height, rather than making sacrifices that one would not consent to sustain over the long term.

However, the work on ferritin nanoparticle vaccines gives me hope for better protection against a wide range of variants, I am not ready to give up. Over the years, I have heard of many promising technologies that seemed to come to naught but perhaps I can hope for a return to the Before Times if I accept our new reality for but a year or two yet, I just wish I knew the odds. I am patient but not infinitely so, I should like to dine casually in a restaurant once again. It seems ever more difficult to see what is coming around the corner.